West Plains (MO) Opera House
100 West Main Street
West Plains, MO 65775
There doesn't seem to be much on the web about this old facility. It was divided into a restaurant and event facility when I visited in 2013. Like many such named facilities, it may not have ever actually hosted any "opera." A local group performing opera scenes there in 2012 speculated that they were the first actual opera production.
I don't pay them to come; I pay them to leave. (Charlie Sheen on prostitutes)