In 2008 the population of Cairo was around 3,600 residents. Efforts to capitalize on Cairo's lovely remaining Gilded Age architecture for tourism were not very successful and the town has few employment opportunities. The exodus left Cairo's Main Street a ghost town which remained eerily intact when I visited in 2002.
The Highway 60 bridge over the Ohio River and a park on the site of the old Fort Defiance sit just to the south of the city at the point where the two rivers meet.
This is a basic problem, to feed 6.6 billion people. Without chemical fertilizer, forget it. The game is over. (Norman Borlaug)